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ALL Drug Updates

Stay up to date with all the latest drug and trial news reported from our X account.

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🚨 NEWS 🚨 The CHMP of the EMA has recommended the approval of obecabtagene autoleucel for the treatment of patients aged β‰₯26 years with relapsed/refractory B-ALL, based on data from the phase Ib/II FELIX study. https://loom.ly/RVyVUL4 #ALL #ALLsm #leusm #MedNews @EMA_News
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🚨 NEWS 🚨 The UK Medicines and Healthcare products Regulatory Agency granted conditional marketing authorization to obecabtagene autoleucel, an autologous anti-CD19 CAR T-cell therapy, for the treatment of adult patients with R/R B-ALL. Read more hereπŸ‘‰ https://loom.ly/IgpypQo #leusm #ALLsm #MedNews
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🚨 News 🚨 NICE recommends blinatumomab with consolidation chemotherapy for patients with Phβˆ’ CD19+ MRDβˆ’ B-ALL in the UK. Read more: https://loom.ly/mbukx0w #leusm #ALLsm #MedNews
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🚨 News 🚨 Olverembatinib granted Breakthrough Therapy Designation by China’s NMPA CDE for the treatment of patients with ND Ph+ ALL in combination with low-intensity chemotherapy. Read more: https://loom.ly/ukDrlJE #MedNews #leusm #ALLsm
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🚨 News 🚨 @US_FDA clears an IND application for CTD402, a CD7-targeted universal CAR T-cell therapy, for the treatment of pediatric and adult patients with R/R T-ALL/LBL. Read more: https://loom.ly/cLDTYEs #MedNews #leusm #ALLsm
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🚨 NEWS 🚨  The European Commission approved blinatumomab, a bispecific T-cell engager, as part of consolidation therapy for the treatment of adult patients with newly diagnosed Phβˆ’ CD19+ B-ALL.  Read more here: https://loom.ly/GWnSrVw#leusm #ALLsm #MedNews
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🚨 NEWS 🚨 @US_FDA has approved an oral solution formulation of imatinib to treat certain forms of leukemia including #ALL, CML, MDS/MPD, and gastrointestinal tumors. πŸ‘‰ https://loom.ly/ab29hIc #ALLsm #leusm
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🚨 NEWS 🚨 @US_FDA approves revumenib for the treatment of pediatric patients aged β‰₯1 year with R/R ALL and a KMT2A translocation. This approval was based on results from the multicenter, open-label AUGMENT-101 study. Read more: https://loom.ly/3XbhErU #allsm #leusm #MedNews
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🚨 NEWS 🚨 The @US_FDA expands oral methotrexate approval to include the treatment of pediatric patients with acute lymphoblastic leukemia. Read more here πŸ‘‰ https://loom.ly/ECfdwnU #ALLsm #leusm #MedNews #MedEd
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🚨 NEWS 🚨 The @US_FDA grants Investigational New Drug application status to VNX-101, a gene therapy product candidate, for the treatment of #ALL. A phase I/II trial of VNX-101 will start enrolling patients in the Q4 of 2024 πŸ‘‰ https://loom.ly/h9fzOko #allsm #leusm #MedNews
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🚨 NEWS 🚨 Topline data from a real-world study of ORG-101, a CAR T-cell therapy, showed positive efficacy and safety outcomes in patients with CD19+ B-cell #ALL. Read the key data here: https://loom.ly/7AYuiio #ALLsm #leusm #MedNews
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🚨 NEWS 🚨 The @US_FDA grants orphan drug designation to alemtuzumab, an anti-CD52 antibody, as part of the lymphodepletion regimen for the treatment of relapsed/refractory B-cell #ALL. πŸ‘‰ https://loom.ly/xouUNJ4 #ALLsm #leusm #MedNews
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🚨 NEWS 🚨 The @US_FDA grants orphan drug & rare pediatric disease designation status to UCART22, an allogeneic CAR T-cell product candidate targeting CD22, for the treatment of #ALL based on data from the phase I/2 BALLI-01 trial πŸ‘‰ https://loom.ly/SBIU_48 #allsm #leusm #MedNews
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🚨 NEWS 🚨 @US_FDA grants rare disease designation to SLS009, an investigational highly selective CDK9 inhibitor, for the treatment of pediatric ALL based on the favorable safety profile of SLS009 in clinical trials. Read more πŸ‘‰ https://loom.ly/8UVxgeY #ALLsm #leusm #MedNews
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🚨 NEWS 🚨 @US_FDA approves blinatumomab for patients aged β‰₯1 month who have CD19-positive, Ph– B-ALL in the consolidation phase, irrespective of MRD status, based on results from the phase III ECOG-ACRIN E1910 study. Read more here: https://t.co/ud3RhkLn0I #ALL #ALLsm #leusm