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Is the anti-CD19 CAR-T brexu-cel safe and effective in B-ALL?

During the 2021 ASCO Annual Meeting and the EHA 2021 Virtual Congress, the ALL Hub spoke with Bijal Shah, Moffitt Cancer Center, Tampa, US. We asked, Is the anti-CD19 CAR-T brexu-cel (formerly KTE-X19) safe and effective in B-ALL?

Is the anti-CD19 CAR-T brexu-cel safe and effective in B-ALL?

Shah evaluates safety and efficacy data from the ZUMA-3 study, evaluating brexu-cel in adult patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL). He focuses on contextualizing these results in comparison with previously approved regimens.