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Ilaria IacobucciDuring the 25th Congress of the European Hematology Association (EHA), the ALL Hub spoke to Ilaria Iacobucci, St. Jude Children's Research Hospital, Memphis, US. We asked, What are the new subtypes in pediatric ALL?
What are the new subtypes in pediatric ALL?
Previously, classification of ALL relied on classic karyotyping and molecular cytogenetic techniques, such as fluorescence in-situ hybridization. However, up to 50% of patients were 'unclassified', making treatment decisions difficult. Novel techniques, such as next-generation sequencing, have allowed classification of these patients while identifying new subtypes of ALL.
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