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What are the strategies to optimize outcomes in pediatric/AYA patients receiving CAR T-cells?

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Charles MullighanCharles MullighanFranco LocatelliFranco LocatelliJosé María RiberaJosé María RiberaAndrea BiondiAndrea BiondiElias JabbourElias Jabbour

Dec 21, 2023

Learning objective: After reading this article, learners will be able to cite new clinical developments in ALL.


During the ALL Hub Steering Committee meeting, Charles Mullighan chaired a discussion on “What are the strategies to optimize outcomes in pediatric/AYA patients receiving CAR T-cells?”, featuring Elias Jabbour, Franco Locatelli, José María Ribera, and Andrea Biondi.

The key discussion topics included:

  • Key factors associated with CAR T-cell therapy success or failure
  • Optimal timing of CAR T-cell therapy
  • Emerging CAR T-cell therapy approaches
  • How to manage relapse after CAR T-cell therapy
  • Issues that should be considered when optimizing CAR T-cell therapy outcomes in pediatric/adolescent and young adult patients

What are the strategies to optimize outcomes in pediatric/AYA patients receiving CAR T-cells?

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