What are the strategies to optimize outcomes in pediatric/AYA patients receiving CAR T-cells?

During the ALL Hub Steering Committee meeting, Charles Mullighan chaired a discussion on “What are the strategies to optimize outcomes in pediatric/AYA patients receiving CAR T-cells?”, featuring Elias Jabbour, Franco Locatelli, José María Ribera, and Andrea Biondi.

The key discussion topics included:

• Key factors associated with CAR T-cell therapy success or failure
• Optimal timing of CAR T-cell therapy
• Emerging CAR T-cell therapy approaches
• How to manage relapse after CAR T-cell therapy
• Issues that should be considered when optimizing CAR T-cell therapy outcomes in pediatric/adolescent and young adult patients