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During the ALL Hub Steering Committee meeting, members discussed ongoing research to address unmet needs in the assessment and management of unusual and severe toxicities, in in both pediatric and adult acute lymphoblastic leukemia. This discussion was chaired by Kjeld Schmiegelow and featured Helene Hallböök, José María Ribera, Anita Rijneveld, André Baruchel, Oliver Ottmann, and Charles Mullighan.
What unusual toxicities are seen in patients with ALL and what are the best strategies to manage them?
The key unmet needs identified include global uniformity in the definition and management of unusual toxicities, evaluation of the long-term effects in patients experiencing toxicities, and re-exposure to novel therapies following toxicities.
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