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Could ponatinib + blinatumomab substitute chemo + allo-HSCT as frontline therapy for Ph+ acute lymphoblastic leukemia?

Featured:

Nicholas J. ShortNicholas J. Short

Sep 4, 2021


During the 2021 ASCO Annual Meeting, the ALL Hub spoke with Nicholas Short, MD Anderson Cancer Center, Houston, US. We asked, Could ponatinib + blinatumomab substitute chemo + allo-HSCT as frontline therapy for Philadelphia-positive (Ph+) ALL?

Could ponatinib + blinatumomab substitute chemo + allo-HSCT as frontline therapy for Ph+ ALL?

Short presents promising safety and efficacy data from a single-arm phase II study investigating a combination of ponatinib + blinatumomab, in adult patients with newly diagnosed or relapsed/refractory Ph+ ALL

 

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