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Chromosomal aberrations
Chromosomal aberrations
Certain subtypes of acute lymphoblastic leukemia (ALL) can be further distinguished by abnormalities in the karyotype that are detected using methods of cytogenetic analysis. Based on chromosomal aberrations, classifications such as Philadelphia chromosome-positive ALL, hyperdiploidy, and KMT2A/MLL allow to assess risk of relapse and can provide the basis for treatment decisions.