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2025-02-19T09:05:37.000Z

Visual abstract | Real-world use of blinatumomab in adult ALL

Feb 19, 2025
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Learning objective: Recall data for emerging therapies for ALL including mechanism of action, safety efficacy, and appropriate patient populations and sequencing.

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Test your knowledge! Take our quick quiz before and after you read this article to find out if you improved your knowledge. Results help us to improve content and continually provide open-access education.

The ALL Hub is pleased to present a visual abstract summarizing results from the NEUF study and other real-world studies assessing the efficacy of blinatumomab in adult patients with B-cell acute lymphoblastic leukemia (B-ALL).

These studies confirmed the efficacy of blinatumomab in real-world patients with B-ALL, including measurable residual disease-positive patients, relapsed/refractory patients, patients in first and second complete remission, and newly diagnosed patients.13


 

Visual Abstract

To download this visual abstract, click below.

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I commit to reviewing the latest clinical data and recommendations for the optimal use of blinatumomab in adult patients with B-ALL.
1 vote - 85 days left

This educational resource is independently supported by Amgen. All content is developed by SES in collaboration with an expert steering committee; funders are allowed no influence on the content of this resource.

  1. Boissel N, Chiaretti S, Papayannidis C, et al. Real-world use of blinatumomab in adult patients with B-cell acute lymphoblastic leukemia in clinical practice: Results from the NEUF study. Blood Cancer J. 2023;13(1):2. DOI: 1038/s41408-022-00766-7
  2. Urbino I, Lengliné E, Rabian F, et al. Blinatumomab consolidation for adult B-cell acute lymphoblastic leukemia in first and second complete remission. Blood Adv. 2024;8(10):2405-2409. DOI: 1182/bloodadvances.2023012139
  3. Zhou H, Wu X, Yang Z, et al. Real-world evidence on treatment pattern, effectiveness, and safety of blinatumomab in Chinese patients with B-cell acute lymphoblastic leukemia. Invest New Drugs. 2024;42(3):299-308. DOI: 1007/s10637-024-01435-1

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